- Multiform psychic pictures - (a) Simple demented type - Memory defect, impairment of judgement and lability of mood going on to imbecility. (b) Gran

. Terminal stage or period of decline - Fits, sometimes with transient neurological deficits may accompany deterioration or occasionally herald it. Motor signs gradually appear until the Insane' patient becomes gradually paralysed, mute and incontinent. Death from intercurrent infection is common SIGNS - (i) Pupillary abnormalities often of Argyll-Robertson type. (ii) Cranial nerves - Optic atrophy much less common than in tabes. Coarse tremors of facial, labial and tongue muscles. (iii) Slurred and tremulous speech, micrographia and inability to write in straight line. (iv) Exaggerated deep reflexes, plantars extensor. (v) Tabes dorsalis may co-exist (Taboparesis). CSF -Moderate pleocytosis, 15-100 cells per c.mm, increased protein and positive antibody tests. Tabes dorsalis CLINICAL FEATURES: Basic lesion - is in the root entry zone of the posterior nerve roots and there is ascending degeneration of the posterior columns, diagnostic features are referable to these 1.