THEORES OF CAUSATION - There is now substantial evidence that schizophrenia is, at least in part.

failure 4 Endocrine disorders - Hypogiycernis. hyperthyroidsm 5 Systemlc infections - Seticemia. axanthamata. 6, Intracramal infections - Menlngitis,. encephatllam, 7. Other intracranial causes - Space occupying lelisons, raised intracranial tension . 8 Head injury (concussion). .9 .NutntionaJ and vitamin delclency - Thiamne. nicotinc acid cyanocobaLamine 10 Epilepsy - Status aplleptcus. poei-tcial statea .Types of functlonal psycnosis. I. Scnizophrenia. It Scnizopnrerrform dsoider. III. Brief reacitva psychosis. IV. Schizo-allective disorder .V Paranoid disorders. I, Schlzophirania Kraepalln in 1896 racognload Ithis form of Iliness and colned tha term ~Dementia Precox' '' (premature deterioration of metnal lacultiss) Bleufer in 1911 introoduced the term schizophrenia (splitinig ot rnind) to identility the same liness Many of the symptoms of schizophrenia seem to result from a breakdown In the mental processes by which we differented our inner selfl from the outside world. To a normal person. thinking, speaking and hearing are quite different subjdctive experiences, but in schtzophrenia. this differentiation becomes blurred Etiology 1. AGE - Peak incidence is between 20-40 years 2 SEX -Equal incidence in both sexes 3 THEORES OF CAUSATION - There is now substantial evidence that schizophrenia is, at least in part. a disorder of neurodevelopment CT and MRI have demonstrated That a significant proportion of pts have lateral vertricular enlargement.cortical suical widening and raduced temporal lobe volumes Some studies in children who subsequently developed schizophrenia show that these children have more postural and movement abnormalities than normal children. Such